PMID: Pharm Biol. 2016 Jul 19:1-7. Epub 2016 Jul 19. PMID: 27436527 Abstract Title: Assessment of bioactive metabolites and hypolipidemic effect of polyphenolic-rich red cabbage extract. Abstract: CONTEXT: Cardiovascular disease is the leading cause of death worldwide and the consumption of red cabbage (Brassica oleracea var. capitata f. rubra DC. - Brassicaceae) has been linked with the reduction risk of chronic diseases.OBJECTIVE: The present study assesses the bioactive metabolites and hypolipidemic effect of red cabbage on rats.MATERIALS AND METHODS: The content of total phenols, flavonoids, anthocyanins, carotenoids, ascorbic acid and antioxidant capacity were assessed, while individual phenolic acids and flavonoids were detected using reverse phase-high performance liquid chromatography (HPLC) analysis. Acute hypolipidemic activity of aqueous extract of red cabbage (RC - 125, 250 and 500 mg/kg) was investigated using a Triton WR-1339 (400 mg/kg) induced hyperlipidemic Wistar rats compared to fenofibrate (65 mg/kg).RESULTS: The HPLC analysis of extracts revealed eight phenolic acids, gallic, protocatechuic, p-hydroxybenzoic, m-coumaric, syringic, caffeic, cinnamic, dicaffeoylquinic and three flavonoids, epicatechin, epigallocatechin, gallocatechin. Furthermore, the aqueous extract showed higher amounts of total phenolics (116.00 mg/g), flavonoids (161.32 μg/g) and, antioxidant activity (87.19%) than the hydromethanolic (89.33 mg/g, 123.34 μg/g and 75.07%), respectively. The RC significantly (p
via Health News Spirulina http://www.greenmedinfo.com/article/red-cabbage-demonstrated-beneficial-effect-against-hypercholesterolemia-and-hy
via Health News Spirulina http://www.greenmedinfo.com/article/red-cabbage-demonstrated-beneficial-effect-against-hypercholesterolemia-and-hy