PMID: Exp Ther Med. 2016 Aug ;12(2):683-689. Epub 2016 Jun 2. PMID: 27446261 Abstract Title: Effect of Lycium bararum polysaccharides on methylmercury-induced abnormal differentiation of hippocampal stem cells. Abstract: The aim of the present study was to observe the effects of a general extract of Lycium bararum polysaccharides (LBPs) on methylmercury (MeHg)-induced damage in hippocampus neural stem cells (hNSCs). The hippocampal tissues of embryonic day 16 Sprague-Dawley rats were extracted for the isolation, purification and cloning of hNSCs. Following passage and proliferation for 10 days, the cells were allocated at random into the following groups: Control, LBPs, MeHg and MeHg + LBPs. MTT and microtubule-associated protein 2 (MAP-2)/glial fibrillary acidic protein/Hoechst immunofluorescence tests were performed to detect the differentiation and growth of hNSCs in the various groups. The differentiation rate of MeHg-treated hNSCs and the perimeter of MAP-2-positive neurons were 3.632±0.63% and 62.36±5.58 µm, respectively, significantly lower compared with the control group values of 6.500±0.81% and 166±8.16 µm (P
via Health News Spirulina http://www.greenmedinfo.com/article/goji-polysaccharides-may-be-considered-be-potential-new-treatment-mehg-induced
via Health News Spirulina http://www.greenmedinfo.com/article/goji-polysaccharides-may-be-considered-be-potential-new-treatment-mehg-induced