PMID: Drug Alcohol Depend. 2016 Aug 5. Epub 2016 Aug 5. PMID: 27522535 Abstract Title: Sex-dependent effects of cannabis-induced analgesia. Abstract: BACKGROUND: Preclinical studies demonstrate that cannabinoid-mediated antinociceptive effects vary according to sex; it is unknown if these findings extend to humans.METHODS: This retrospective analysis compared the analgesic, subjective and physiological effects of active cannabis (3.56-5.60% THC) and inactive cannabis (0.00% THC) in male (N=21) and female (N=21) cannabis smokers under double-blind, placebo-controlled conditions. Pain response was measured using the Cold-Pressor Test (CPT). Participants immersed their hand in cold water (4°C); times to report pain (pain sensitivity) and withdraw the hand (pain tolerance) were recorded. Subjective drug ratings were also measured.RESULTS: Among men, active cannabis significantly decreased pain sensitivity relative to inactive cannabis (p
via Health News Spirulina http://www.greenmedinfo.com/article/these-results-indicate-cannabis-smokers-men-exhibit-greater-cannabis-induced-a
via Health News Spirulina http://www.greenmedinfo.com/article/these-results-indicate-cannabis-smokers-men-exhibit-greater-cannabis-induced-a