PMID: BMC Complement Altern Med. 2015 ;15:294. Epub 2015 Aug 25. PMID: 26303848 Abstract Title: The effects of Malaysian propolis and Brazilian red propolis on connective tissue fibroblasts in the wound healing process. Abstract: BACKGROUND: To evaluate and compare the effects of ethanolic extracts of Malaysian propolis and Brazilian red propolis at different concentrations on the migration and proliferation of fibroblast cells.METHODS: Malaysian and Brazilian red propolis crude samples were extracted using ethanol. Their wound healing effects were tested in vitro on the normal human fibroblast cell line CRL-7522. Cell migration and proliferation assays were carried out using propolis concentrations of 1, 10, 100, 250, 500 and 1000μg/mL. The data were analyzed using one-way ANOVA and post hoc Bonferroni tests (α=0.05).RESULTS: Malaysian and Brazilian red propolis followed a concentration-dependent increasing and decreasing trend. Malaysian propolis showed the fastest migration rate at 250μg/mL which was statistically significant (p0.05) compared to control. Brazilian red propolis showed a slight increase in migration and proliferation at 10 and 100μg/mL, respectively with no significant difference (p>0.05) compared to control, while concentrations above these conferred inhibitory effects.CONCLUSION: Malaysian and Brazilian red propolis show potential to assist in wound healing, depending on their concentration.
via Health News Spirulina http://www.greenmedinfo.com/article/malaysian-and-brazilian-red-propolis-show-potential-assist-wound-healing
via Health News Spirulina http://www.greenmedinfo.com/article/malaysian-and-brazilian-red-propolis-show-potential-assist-wound-healing